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Wouldn't it be great if we could predict the future? We could invest wisely, prepare for social change, and have next season's fashionable footwear.

But in our accelerated world, it seems increasingly difficult to figure out what the next big thing will be. In this hour, are trends a...Read more

To The Best Of Our Knowledge

Michael Chabon's a pretty successful writer of literary fiction. As far as he's concerned, literary fiction is just another genre, with its own set of conventions. In this hour of To the Best of Our Knowledge, we get into the fight over genre fiction. Agatha Christie's grandson says the...Read more

To The Best Of Our Knowledge

The average American spends more time on Facebook than with their pets or exercising -- and that's not counting Twitter, Instagram, or Vine. We're more connected than ever these days, but at what cost?Read more

To The Best Of Our Knowledge

It's been said that "Writing about music is like dancing about architecture." But the rock critic Robert Palmer didn't have any trouble. Palmer wrote effortlessly about all kinds of music – rock and roll, blues, jazz and world music. The fact that Palmer was also a musician didn't hurt. In...Read more

To The Best Of Our Knowledge

We’re all seeking something.  What about you? What are you looking for?Read more

To The Best Of Our Knowledge

Anne D. LeClaire was walking along the beach on Nantucket Sound when she heard a voice. The voice said, "Sit in silence." LeClaire turned to look but there was no one there. Anne D. LeClaire talks about this experience seventeen years ago and how it inspired her to remain silent for two days...Read more

To The Best Of Our Knowledge

Imagine the world as we know it, only without us. In this hour of To the Best of Our Knowledge, a writer imagines a world reinventing itself without human beings. He sees the New York subway system returning to its watery origins. The re-absorption of carbon into the earth, and endangered...Read more

a man near the Mississippi

The Mississippi River is an American icon. It's a body of water that’s been shaped as much by cultural processes as by environmental ones. From the state lines it draws to its role in literature and the arts, it’s a river that flows deep in the American psyche.

This episode is about the...Read more

To The Best Of Our Knowledge

Subdivisions. Industrial Parks. Strip Malls. Gridlock. Sprawl is socially unequal, environmentally irresponsible, and aesthetically ugly. Right? We'll look at the costs and, YES, the benefits of suburban sprawl. Because maybe, just maybe, sprawl is a good thing.Read more

To The Best Of Our Knowledge

Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more

To The Best Of Our Knowledge

Would you recognize a genius if you met one?  We’ll introduce you to four geniuses – or at least four people who just landed MacArthur “genius" awards: classical pianist Jeremy Denk, jazz musician Vijay Iyer, fiction writer Karen Russell and astrophysicist Sara Seager.  Also, practical tips on...Read more

To The Best Of Our Knowledge

John Brown was a terrorist, a man who led a raid in Kansas that butchered five unarmed men. He was also, arguably, of the few white people in 1850s America who was totally color blind. According to a new book he was "the man who killed slavery and sparked the Civil War." So, was John Brown a "...Read more

To The Best Of Our Knowledge

The Meaning of Life

Part Four

 

Pete Best should have been famous beyond his wildest dreams. He had Ringo's job just months before the Beatles' "Love Me Do" became a smash hit. But he got tossed out of the band and ended up working...Read more

To The Best Of Our Knowledge

Charles Monroe-Kane grew up hearing voices in his head. For years he tried to drown them out with potentially lethal quantities of hard drugs and alcohol. Lithium saved his life but coming clean about his past hasn't been easy. How do you admit, as a public radio producer, that for years you had...Read more

To The Best Of Our Knowledge

Many people treat it as a national holiday, more Americans watch it than vote in presidential elections, and it leaves an economic footprint larger than the Gross Domestic Product of 49 countries: it's Super Bowl Sunday. In this hour of To the Best of Our Knowledge, we'll go behind the scenes of...Read more

To The Best Of Our Knowledge

A year and a half ago Gary Wolkstein’s doctor told him he had cancer of the spine, that it was terminal, and that he had just a few months left to live.  Today Gary’s in fine health.  Not, it wasn’t a miracle cure, it was a mistake.  In this hour of To the Best of Our Knowledge,...Read more

To The Best Of Our Knowledge

From Soup to Nuts:

Part Two

This may be the century when Americans forget how to cook. We're just too busy. Take-out's too easy. And, who needs to cook when you can buy ready-made...Read more

To The Best Of Our Knowledge

Remember the good old days? No? Well that's either because you haven't lived them yet, or you need to check the note you left on the bedside table. In this hour of To the Best of Our Knowledge, we're looking at age and memory with a Nobel Prize winner searching through the mechanics of the brain...Read more

To The Best Of Our Knowledge

The Creative BrainCreativity is a little like obscenity:  You know it when you see it, but you can't exactly define it....unless you're a neuroscientist.  In labs around the...Read more

To The Best Of Our Knowledge

There’s another September 11th.  On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende.  Newly declassified documents show the C.I.A.’s extensive involvement in the coup.  On this hour of To the Best of Our Knowledge, the Pinochet file.  Also,...Read more

To The Best Of Our Knowledge

You know those end of the year lists?  Best books, movies, music and so on?  This hour, To the Best of Our Knowledge shares the best interviews from 2015.  Plus a booklist or two.Read more

a preacher on the prairie

You know the earth is round, the sky is up, and your dog loves you.  But HOW do you know those things?  This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more

To The Best Of Our Knowledge

Computers permeate our lives.  They scan our groceries.  They entertain us.  They keep us safe.  But, can they write a poem?  In this hour of To the Best of Our Knowledge, will your desktop be the next Bard?  And, the life of the original rock n’ roll rebel: the 19th century French poet Arthur...Read more

To The Best Of Our Knowledge

Her novel “Bel Canto” was a hit so now novelist Ann Patchett is a star.  But back when they were in college, it was her fellow student Lucy Grealy who got treated like a rock star.  In this hour of To the Best of Our Knowledge, a look at uncommon friendships.  Ann Patchett tells how her...Read more

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