Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Suppose you drop a family photograph on the subway, is it still yours? Not if Brian Dunn finds it. He collects lost photos and makes them his own. I’m Jim Fleming. Next time on To the Best of Our Knowledge “Who owns what?” If there are copyrights are there copy “...Read more
It's been more than four decades since the Civil Rights movement ended racial segregation in America. Yet few would say African-Americans are now fully integrated – or assimilated. In this hour of To the Best of Our Knowledge, African American writers talk about race, and how black history –...Read more
Neuroscientists have made remarkable discoveries about the brain, but so far, no one's come close to cracking the biggest mystery of all - the connection between the...Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
Kashmir has been called the most beautiful place on earth. Today, it’s the melting point for a bitter dispute between India and Pakistan. It’s a situation that’s been called more dangerous than the Cuban missile crisis. In this hour of To the Best of Our Knowledge, an Indian writer mourns the...Read more
One of this year's big novels is Colson Whitehead's sweeping historical novel, "The Underground Railroad." It's an unflinching look at the experience of slavery, inspired by the classic slave narratives. And being a sci-fi geek, Whitehead also weaves in bits of fantasy, creating an alternative...Read more
What would a secular society really look like? We take an unconventional look at religion, the fiction it inspires, and reflect on why William James' classic book on mysticism, "The Varieties of Religious Experience," still matters.Read more
David Rothenburg is a philosopher and a jazz clarinetist, who also loves birds. So one day he sat down in the National Aviary in Pittsburgh and started playing music. Lo and behold, a white-crested laughing thrush started singing with him, riffing on the tunes he played. Since then Rothenburg...Read more
What are the great country music singles? Patsy Cline’s “Crazy,” probably. George Jones’ “slobbing tearjerker,” “He Stopped Loving Her Today.” What about the Rolling Stones’ “Honky Tonk Women”? and Otis Redding’s “(Sittin’ On) the Dock of the Bay? According to the book “Heartaches by the...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Poet Nick Lantz has a darkly satirical take on American culture. Lately, he’s been thinking about political spin and how politicians speak. In this interview—the third in our series ...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
What if our lives were like DVDs? What if we had alternative endings to look forward to, instead of death? We explore our lust for immortality. And we look at the many alternative endings that Ernest Hemingway wrote for his classic novel, "A Farewell to Arms."
For National Poetry Month, To The Best Of Our Knowledge celebrated poetry with original work by five leading American poets, written in response to current events.Read more
Ever dream of finding buried treasure? In this hour of To the Best of Our Knowledge, real-life treasure hunters like the two small-time prospectors who risked their lives in the Canadian tundra, and found one of the world’s biggest diamond mines. Also, hunting for dinosaur bones in the Gobi...Read more
Everybody needs a little help, and some of us need a lot. In this hour of To the Best of Our Knowledge, we’ll meet some helpers - and they’re not all human. We’ll visit a stable where they do equine assisted therapy, and we’ll hear from a writer who’s a volunteer fireman in his small hometown...Read more
When he was 10-years-old, Brian Raftery realized he couldn't sing. Despite his lack of vocal prowess, Raftery is obsessed with karaoke. He's traveled around the world to trace karaoke's evolution from a cult fad to a multimillion-dollar industry. In this hour, we'll explore the world of karaoke...Read more
Bohemians used to hate anything that reeked of money. It destroyed the soul. Now, many self-styled bohemians are reveling in slate shower stalls, Range Rovers, and lava-rock grills. In this hour of To the Best of Our Knowledge, the triumphs of the “Bobo” – the Bourgeois...Read more
The Capitol Hilton. The Eve of then-President Clinton’s Alfalfa Club Speech, one of four humorous speeches of the so-called Washington “silly season.” In this hour of To the Best of Our Knowledge, the story of a White House joke-writer, a contentious egg-timer, and the night Bill Clinton...Read more
Suppose there's a pill that would dramatically boost your creativity. Would you take it? Psychologist Jim Fadiman says that pill exists. It's the powerful hallucinogen LSD. Fadiman describes a remarkable experiment showing how psychedelics enhanced the creativity of senior scientists. Read more
Nerds are an easy target for humor in movies and on TV... with their thick black glasses, hopelessly out-of-fashion clothes, and over-enunciated diction. But there's a dark side to nerds. In this hour of To the Best of Our Knowledge, we'll find out how the nerd stereotype is harming our children...Read more
Fifty Years ago James Watson and Francis Crick made history when they cracked the code for DNA. Watson was only 24 years old, and by no means the smartest scientist around. So why do some scientists make great discoveries? In this hour of To the Best of Our Knowledge, James Watson talks about...Read more
Everyone in your Facebook feed is falling for fake news–sharing it even when there's no way it can be true. They keep falling for it. But not you, right? You’re smart, well-educated. You can tell the difference. Or can you?Read more