Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
For National Poetry Month, To The Best Of Our Knowledge celebrated poetry with original work by five leading American poets, written in response to current events.Read more
Modern medicine can treat disease at a molecular—or even atomic – level. And today’s surgeons can fix things the naked eye can’t even see. But there’s one thing every patient wants that no technology in the world can provide: compassion. In this hour, doctors talk about the...Read more
The Back to the Land spirit of the 60s lives on today, in the proliferation of farmer's markets, and the increased interest in sustainability and growing our own food. From the fight to end food waste in America to the art of living small, we'll find out what the Back to the Land spirit...Read more
Future Perfect: Dreamers, Schemers & Visionaries
Part Three
Our environment is in trouble. It's not hard to imagine global catastrophe as problems like climate change and overpopulation take their toll. But there's always hope...Read more
Whether black from a bottomless cup or as a Frappuccino mocha skim latte, it’s our culture’s elixir, coffee. In this hour of To the Best of Our Knowledge, java, joe, or a cup of mud. Most of us drink it everyday, but few of us know the effects it has on the world’s economy, or even...Read more
Ben Franklin, Henry Ford, Abigail Adams, Elvis Presley. Know what they have in common? They're all on Daniel Wolff's list of great Americans. Wolff explains the unique ways those people learned what they had to know. We'll also take a hard look at IQ and its relationship to race and class, and...Read more
As soon as you, or someone you love, has that first "senior moment" – you start to worry. Is this the beginning of the slippery slope of Alzheimer's Disease? Relax! There's something you can do. The good news is that most of us won't live long enough to get Alzheimer's. And the rest of us...Read more
Do you remember the first time you saw a piece of art or heard a piece of music that shocked you? Something you immediately knew your parents would hate? Remember how good it felt, to like something bad? In this show, we're talking about shock value — the virtues of transgressive, subversive...Read more
America was once a nation of readers, but now experts warn that reading is in decline as our cultural life moves online. In this hour of To the Best of Our Knowledge, an hour in praise and defense of the book. Ursula Le Guin takes book publishers to task and a beloved children's book editor...Read more
Trayvon Martin’s death and George Zimmerman’s acquittal has sparked a debate over race this country hasn’t seen in many years. So, whose America is it? The young black teen in a hoodie? The illegal immigrant who’s been living here for twenty years? Muslims? Native Americans? You?Read more
When Charles Mingus died, his widow took his ashes to India and scattered them in the Ganges. But that wasn’t the end. In this hour of To the Best of Our Knowledge, Sue Mingus talks about the legacy of her late husband’s music: his spirituality, his anger, and his love. Also, a conversation...Read more
A car accident at twenty-one left John Callahan paralyzed. He’s become a very successful cartoonist -- poking fun at disabilities and the idiosyncrasies of life. His work has been described as “rude, shocking, tasteless, and depraved” – by his fans. Next time on To...Read more
East Meets West
Part Three
The ancient trading routes through Persia, India and China were once the crossroads between East and West. Is the blogosphere the new Silk Road? Hear heartrending e-mails between an American professor and...Read more
It’s Oscar season and Hollywood is once again celebrating the best films of the year. It would seem that we're a nation obsessed with movies. As a country, we spend billions of dollars to watch them every year, and celebrate them with a variety of awards ceremonies. But what separates a...Read more
In case it’s not obvious: we LOVE books on TTBOOK. But we’re also incredibly picky about which books we choose for interviews.Read more
Spiderman had a pretty good summer last year, but J.K. Rowling wasn’t worried. When the sixth Harry Potter book came out, children trampled the web-slinger in their rush to bookstores and libraries. Which makes perfect sense to author and Arthurian scholar Jane Yolen. She says it’s all about...Read more
The parallels between the recent financial meltdown and that of 1929 are striking. In both cases a financial bubble burst and led to a run on the banks. Both times the Federal Reserve made huge mistakes. So how close did we come to another Great Depression? In this hour of To the Best of Our...Read more
After World War Two, existentialism was all the rage in the U.S.A. College students rebelled by smoking European cigarettes and wearing black clothes and berets. Jean-Paul Sartre and Albert Camus felt that Americans were too self-confident and superficial to accept this dark, brooding...Read more
Philosophers get a bad rap - they're written off as too academic, too detached from daily life. But we're seeing a philosophy revival, from philosophy cafes to philosophers as therapists. From the Stoics to Spinoza, an argument for why philosophy still matters.Read more
Patty Loveless is a coal miner’s daughter. And a country singer, just like her distant cousin Loretta Lynn. When Patty Loveless’ father contracted black lung disease the family had to move to Louisville, Kentucky – so Patty’s dad could receive medical attention. In this hour of To the Best of...Read more
Bombay is the largest city in the world. And one of the most confounding. Bar dancers, gangs, and Bollywood all call Bombay home, for better or worse. In this hour of To the Best of Our Knowledge, a Bombay-native takes us inside this Maximum City. Also, the writer of the hit movie "Monsoon...Read more
The Baobab looks like an upside down elephant. It’s enormous and gray, with little sprays of green at the top. According to an African creation myth, the Great Spirit gave each animal a gift. The hyena got the baobab and tossed it aside in disgust. But Thomas Pakenham thinks it’s one of the...Read more
Whitney Houston, Celine Dion, Brittney Spears – divas? Nah. Maria Callas – now she was a diva! In this hour of To the Best of Our Knowledge, two great ladies with leather lungs – Maria Callas and Judy Garland – their triumphs and tragedies from Onassis to Oz. And other...Read more