Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
George Burns lived a good long life, hanging on to one hundred. These days scientists say that’s no big deal. According to them, some of us may be tottering around the golf course when we’re 150. In this hour of To the Best of Our Knowledge, the quest for immortality – how long can science...Read more
”Seinfeld” and “The Simpsons” may not look like grist for the philosopher’s mill, but philosopher Bill Irwin says they have a few things to teach us. In this hour of To the Best of Our Knowledge, philosophy from Socrates to Wittgenstein, with a short detour through pop culture. Also...Read more
What would a secular society really look like? We take an unconventional look at religion, the fiction it inspires, and reflect on why William James' classic book on mysticism, "The Varieties of Religious Experience," still matters.Read more
What are the great country music singles? Patsy Cline’s “Crazy,” probably. George Jones’ “slobbing tearjerker,” “He Stopped Loving Her Today.” What about the Rolling Stones’ “Honky Tonk Women”? and Otis Redding’s “(Sittin’ On) the Dock of the Bay? According to the book “Heartaches by the...Read more
Global pandemics, alien invasions, the Second Coming....why do we love imagining the end of the world? We examine apocalyptic thinking – from vampire movies to the Book of Revelation.Read more
Ben Kilham has some unusual playmates - black balls of fur who scratch, wrestle and climb all over him. They are orphaned bear cubs. And Kilham is their surrogate mom. He’s raised two dozen bear cubs and then released them into the wild. Next time on To the Best of Our Knowledge, we’ll trek...Read more
Phil Harvey gives away tens of millions of dollars every year to fight AIDS and promote family planning in such places as India, Brazil, Vietnam and Ethiopia. Where does the money come from? Harvey runs the largest mail-order erotica business in the world. In this hour of To the Best of Our...Read more
It turns out that television may not be quite the "boob tube" and "the idiot box" that we thought it was. It seems that watching TV can actually make you smarter... by posing new cognitive challenges for your brain to solve. In this hour of To the Best of Our Knowledge, we'll explore the...Read more
David Graeber was an iconoclastic anthropologist and influential radical thinker, one who popularized the rallying cry "We are the 99%." He died on Sept. 2 in Venice, Italy at age 59. Read more
Words can change lives. Just look at the “at-risk” students in Erin Gruwell’s class. Many of them were branded “unteachable.” Then they read Anne Frank’s diary, and started to keep their own journals. The experience was electrifying. In this hour of To the Best of...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
Alex Rider, Nancy Drew, The Cat in the Hat, and Harold and the Purple Crayon – for millions of children of all ages, they're some of the most imaginative and mysterious stories around. But as it turns out, the authors sometimes have their own, personal mysteries to share. In this hour of To the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
Nerds are an easy target for humor in movies and on TV... with their thick black glasses, hopelessly out-of-fashion clothes, and over-enunciated diction. But there's a dark side to nerds. In this hour of To the Best of Our Knowledge, we'll find out how the nerd stereotype is harming our children...Read more
After 11 years of isolation in New England, Nathan Zuckerman returns to New York City. Now 71, Zuckerman discovers that a lot has changed. In this hour of To the Best of Our Knowledge, we'll meet Nathan Zuckerman's creator, the renowned novelist, Philip Roth. And we'll find out how both Roth...Read more
What is it about certain films, and certain directors, that inspires obsession? Maybe because these directors are obsessed themselves. Like the legendary filmmaker Werner Herzog, who...Read more
In this hour of To the Best of Our Knowledge, some of the most critical questions you’ll ever face. Who are you? What does your life mean? And how did you decide who you wanted to be? We’ll hear from Rabbi Harold Kushner, Senator John McCain and novelist Tim O’Brien. We’ll talk about making...Read more
As artists and scientists explore the edges of our senses, what we touch, taste, see, smell, and hear is changing.
In this hour we hear from a psychiatrist who’s using touch to help people recover from trauma, investigate a mysterious sensory experience that gives some people euphoric...Read more
Investigative journalist Seymour Hersh made his name when he broke the story of the My Lai Massacre. Looking back you have to wonder: why did Lt. William Calley tell Hersh he’d killed hundreds of Vietnamese civilians? On this hour of To the Best of Our Knowledge Hersh says “because I asked him...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
Siberia is the name for a place we tend to think of as a metaphor as much as a destination on the map. Writer Ian Frazier indulged what he calls his dread Russia love with travels through Siberia, tracing the path of prisoners on their way to lonely exile and through mosquito-ridden swamps at...Read more