Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
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Episode Archives
Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Bohemians used to hate anything that reeked of money. It destroyed the soul. Now, many self-styled bohemians are reveling in slate shower stalls, Range Rovers, and lava-rock grills. In this hour of To the Best of Our Knowledge, the triumphs of the “Bobo” – the Bourgeois...Read more
Suppose there's a pill that would dramatically boost your creativity. Would you take it? Psychologist Jim Fadiman says that pill exists. It's the powerful hallucinogen LSD. Fadiman describes a remarkable experiment showing how psychedelics enhanced the creativity of senior scientists. Read more
You stub your toe, hit your head on an open cupboard, slam your fingers in a car door, slice your hand on the sharp lip of can, or lick an envelope the wrong way. Your toes throbs, your head aches, your fingers pound, your hand hurts, your lip smarts.
Pain is your body’s way of letting...Read more
What would a secular society really look like? We take an unconventional look at religion, the fiction it inspires, and reflect on why William James' classic book on mysticism, "The Varieties of Religious Experience," still matters.Read more
George Burns lived a good long life, hanging on to one hundred. These days scientists say that’s no big deal. According to them, some of us may be tottering around the golf course when we’re 150. In this hour of To the Best of Our Knowledge, the quest for immortality – how long can science...Read more
What are the great country music singles? Patsy Cline’s “Crazy,” probably. George Jones’ “slobbing tearjerker,” “He Stopped Loving Her Today.” What about the Rolling Stones’ “Honky Tonk Women”? and Otis Redding’s “(Sittin’ On) the Dock of the Bay? According to the book “Heartaches by the...Read more
Calling Lynne Cox a swimmer is like calling Mohammed Ali a tough guy. At age fourteen, she swam to Catalina Island from mainland California. At eighteen she swam between the islands of New Zealand. Years later, with miles of hard swims behind her, she turned her eye to the unthinkable - the...Read more
David Rothenburg is a philosopher and a jazz clarinetist, who also loves birds. So one day he sat down in the National Aviary in Pittsburgh and started playing music. Lo and behold, a white-crested laughing thrush started singing with him, riffing on the tunes he played. Since then Rothenburg...Read more
Poet Nick Lantz has a darkly satirical take on American culture. Lately, he’s been thinking about political spin and how politicians speak. In this interview—the third in our series ...Read more
The Capitol Hilton. The Eve of then-President Clinton’s Alfalfa Club Speech, one of four humorous speeches of the so-called Washington “silly season.” In this hour of To the Best of Our Knowledge, the story of a White House joke-writer, a contentious egg-timer, and the night Bill Clinton...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
Ok, take a breath. Close your eyes. Recall the home of your childhood. Can you smell the cookies in the kitchen? Can you open a drawer in your bedroom? Do you see the sunlight through a window? Every building has a story. . . And not only a story, every building has a sound.Read more
Is there such a thing as true, original creativity? Or "Are we just seeing further by standing on the shoulders of giants?", to paraphrase Sir Isaac Newton. In this hour of To the Best of Our Knowledge we'll explore the question of where good ideas come from. Steven Johnson will tell us about...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
Nerds are an easy target for humor in movies and on TV... with their thick black glasses, hopelessly out-of-fashion clothes, and over-enunciated diction. But there's a dark side to nerds. In this hour of To the Best of Our Knowledge, we'll find out how the nerd stereotype is harming our children...Read more
With hundreds of millions of people moving into cities, we're wondering what shapes urban cultures. In this hour, Nobel Laureate Orhan Pamuk talks about how Istanbul shaped his writing. One historian argues that early liberal philosophies from Amsterdam shaped the United States. And we check in...Read more
Fifty Years ago James Watson and Francis Crick made history when they cracked the code for DNA. Watson was only 24 years old, and by no means the smartest scientist around. So why do some scientists make great discoveries? In this hour of To the Best of Our Knowledge, James Watson talks about...Read more
Everyone in your Facebook feed is falling for fake news–sharing it even when there's no way it can be true. They keep falling for it. But not you, right? You’re smart, well-educated. You can tell the difference. Or can you?Read more
Everybody gets excited about whatever's new, but what about what's really, really old? In this hour of To the Best of Our Knowledge we commemorate geologic time. We'll meet the scientists who found the oldest object on Earth - a three point four billion year old zircon! And the Jazz...Read more
“We can be bought,” they said,” but we can’t be bored.” The king and queen of American theater, Alfred Lunt and Lynn Fontanne turned down a fantastic sum from the movies in the middle of the depression to continue to live their illusion on the stage. In this hour of To the Best of Our...Read more