Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
As Cuba and the U.S. restore diplomatic relations, what's in store for Americans who want to visit Cuba? And for Cubans wanting more prosperity? Steve Paulson recently traveled to Cuba and brought back new stories about our island neighbor. From diplomacy to culture, we tackle jazz,...Read more
Forty years ago, the U.S. ended its war in Vietnam, but we're still fighting over its legacy - in foreign policy and military strategy, and also in books and movies. But there's one question Americans rarely ask: what does the war mean to the Vietnamese themselves? We'll hear several...Read more
Leon Fleisher was once one of the world’s great pianists. Then a rare neurological disease left two fingers of his right hand clenched into his palm, and he could play only with his left hand for 37 years. At 76, Fleisher’s miraculously regained the use of his bad hand and he’s playing...Read more
As the Bible famously says, "there is nothing new under the sun." That's pretty bleak. If it's all been said and done before, what's left? In this hour of To the Best of Our Knowledge, remix culture. Digital sampling, audio hacking, mash-ups… In today's music and art it's all about mix and remix...Read more
When Meg Gaines was diagnosed with terminal cancer, her doctor told her to go home and think about the quality, not the quantity, of her days. Instead she grabbed him by the bow-tie and said “I don’t think you understand. I intend to live.” Today Meg Gaines is helping other cancer patients...Read more
Ask any babbling baby. Talking’s fun! At least it is until the grammarians get after you. But Patricia O’Connor says we can all relax, there’s nothing wrong with splitting an infinitive and there never was. In this hour of the Peabody-Award winning program To the Best of Our Knowledge we...Read more
Outsiders used to be the outcasts, misfits, and under-employed. Today, they're indie, alternative and ahead of their time. Outsiders are thriving and they're changing the way we think about what is mainstream and what is alternative. You might even say that outsiders are the new insiders.Read more
We may think it’s pretty clear what is – and isn’t – science, but history is littered with cases where the line wasn’t so obvious. For instance, Isaac Newton studied alchemy, and Galileo was a practicing astrologer. This hour explores the edges of science, and we hear about the...Read more
Linus has his security blanket. Renowned neurologist Oliver Sacks had the Periodic Table of the Elements. In this hour of To the Best of Our Knowledge, My Chemical Life. Oliver Sacks remembers a childhood steeped in chemistry. Also, Primo Levi survives Auschwitz, through chemistry. And,...Read more
Sometimes, a single word speaks volumes about its era. Sputnik conjures up both the heady excitement of the early Space Race and the whole scary history of the Cold War. In this hour, To the Best of Our Knowledge touches on a few of these cultural touchstones....from Sputnik to Snoopy. We'll...Read more
According to a "New York Times" poll he's the third most famous person in Japan, right behind Hirohito and Bruce Lee. But the truth is he's not even a person, he's a giant green, radioactive lizard named Godzilla. In this hour of To the Best of Our Knowledge we'll explore the history of...Read more
The Meaning of Life
Part Three
In this hour of To the Best of Our Knowledge we consider the good stuff. Love. Poetry. Pleasure. Chocolate. Art. Beauty. New York Times Art Critic Michael Kimmelman says the beauty of beauty is that...Read more
A car accident at twenty-one left John Callahan paralyzed. He’s become a very successful cartoonist -- poking fun at disabilities and the idiosyncrasies of life. His work has been described as “rude, shocking, tasteless, and depraved” – by his fans. Next time on To...Read more
It’s Oscar season and Hollywood is once again celebrating the best films of the year. It would seem that we're a nation obsessed with movies. As a country, we spend billions of dollars to watch them every year, and celebrate them with a variety of awards ceremonies. But what separates a...Read more
Here’s the bad news. You can get the thing you most want - a BMW, the winning lottery ticket, and you still won’t be any happier. The good news? You can survive the most devastating catastrophes and you’ll be back on your feet in less time than you think. Next time on To the Best of Our...Read more
Patti Smith revolutionized rock'n'roll in the Seventies by fusing poetry with rock music. Now, she's written a remarkable memoir about her emergence as an artist, and her friendship with photographer Robert Mapplethorpe. In this hour of To the Best of our Knowledge, we'll talk with Patti Smith...Read more
Adventure writer Ann Jones recalls crossing Africa from Tangier to Cape Town in search of one special tribe. They’re guided by the “feminine” principles of compromise, tolerance and peace. Also, Tony Horwitz sets sail in the wake of Captain Cooke. We’ll hear about a Frenchman who never went...Read more
You may recall the story of six young people who reported seeing visions of the Virgin Mary in Medjugorje. Journalist Randall Sullivan talked to one of the visionaries and concluded she believes what she was reporting. But where does that leave us? Next time on To the Best of Our Knowledge,...Read more
Andre Agassi says he always hated tennis, even though it's what made him rich and famous. But maybe that's not surprising, considering how his father used to browbeat him into hitting 2500 balls a day when he was seven years old, and later sent him off to a tennis academy, which Agassi calls a "...Read more
When the Soviet Union fell, China was poised to take over as America’s next great enemy. The 9/11 happened and there was a new enemy. So, what about China? Next time, we’ll take a closer look at China today and what the future holds for US/China relations. Also, a talk with Nobel prize-...Read more
Canal Street flooded with so much water it looks like an actual canal. People mourning the loss of their homes and loved ones. The Gulf Coast will never be the same after the devastation that Hurricane Katrina has caused. In this hour of the Peabody-Award-Winning program To the Best of Our...Read more
Busloads of Senior Citizens roll onto the Reservation for high stakes bingo. Lottery tickets show up on people’s shopping lists in 47 states. Practically every office has a pool on the NFL or the Final Four or the outcome of the latest reality television series. In this hour of To the Best of...Read more
A restaurant wasn't always a place to eat. It used to be a thing to eat - a cup of medicinal broth to restore your health. These days Americans eat almost half their meals out, so how did the modern restaurant evolve? In this hour of To the Best of Our Knowledge, the rise of the restaurant. ...Read more