Shortly after her mother died of ovarian cancer, Jessica Queller had herself tested for the dreaded BRCA gene mutation. She tested positive, which meant she had an 87 percent chance of developing breast cancer, and a nearly 50 percent chance of ovarian cancer. So Queller did the unthinkable: at...Read more
Intelligent. Optimistic. Curious.
Episode Archives
You’re part of the “Freedom Movement,” - a group of anti-globalization anarchists. You’re blowing up security stations to fight “The Corporation.” Sounds like a scene out of Seattle during the World Trade Organization protests of a few years ago, doesn’t it? But it’s not. It’s...Read more
As the Dalai Lama turns 80, we reflect on his legacy and remarkable personal history. Also, how various Eastern spiritual traditions have taken root in the West - from yoga to meditation. And the legacy of California's famous utopian experiment at Esalen and its "religion of no religion."Read more
Kayfabe is an old carny term for fakery. Now it’s the code of honor for professional wrestling. Kayfabe means you never, EVER admit to ANYONE under ANY circumstances that pro wrestling’s fake. In this hour of To The Best Of Our Knowledge - the spectacle of professional wrestling. We’ll talk real...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
A rose by any other name may smell as sweet, but you still need a word to describe that glorious smell. We'll try out new words from the online world with a New York Times language blogger - words like YakkaWow and suicide cuisine. Also, the rise of a new world language called Globish....Read more
Siberia is the name for a place we tend to think of as a metaphor as much as a destination on the map. Writer Ian Frazier indulged what he calls his dread Russia love with travels through Siberia, tracing the path of prisoners on their way to lonely exile and through mosquito-ridden swamps at...Read more
Mary Ann Caws is an internationally respected scholar of surrealism. She has translated many of the movements major texts and is the editor of “Surrealism (Themes and Movements).” Caws talks with Anne Strainchamps about the history of the surrealist movement. Also, we hear actor Steve O’Connell...Read more
Crime may not pay but writing crime fiction does. Just ask the Swedish writer, Henning Mankell. Or those who write "Tartan Noir"...Scottish detective fiction. In this hour of To the Best of Our Knowledge, we'll explore Northern Europe's fictional crime wave. Also, Roger Ebert on film noir.Read more
Do you get eight hours of sleep a night? If not, join the millions of sleep-deprived Americans stumbling through life half-awake. Scientists say our national sleep debt may be behind the epidemics of diabetes and obesity – maybe even cancer. In this hour of To the Best of Our...Read more
Say you’re in Vegas playing high-stakes poker. You haven’t slept in days. To make matters worse, you’re being stared down by two of the best poker players in the world. And...you’re bluffing. So, you bet it all to bring the pot to well over a million dollars. In this hour of To the Best of...Read more
With the emergence of barefoot running, the sport suddenly is red hot again. But barefoot or not, are human bodies really born to run? We'll check in on the science or runner's high this hour, and try to unlock the secrets of the Kenyans - the fastest people on earth. Also, Olympic medalist...Read more
Many Americans think the story of Cuba begins and ends with Fidel Castro. But the soul of the Cuban Revolution belonged to the charismatic, Romantic guerilla hero Ernesto “Che” Guevara. To the Best of Our Knowledge revisits the Sixties and counts the private costs of that era’s social gains. ...Read more
Jacques Derrida and the philosophical movement known as deconstruction were once the rage on college campuses. Those days have passed, but deconstruction's influence is everywhere. We talk with Gayatri Chakravorty Spivak, who first translated Derrida's landmark book "Of Grammatology" into...Read more
Have you ever wished you cared less or been told to develop a thicker skin? For the polite and anxious among us, suddenly being immune to criticism and embarrassment might seem to be a superpower. In this hour, we’re exploring...Read more
Science and the Search for Meaning: Five Questions, Part Two: What Does Evolution Want?
If there’s one strand of evolutionary theory that sticks in the craw of nearly every religious believer, it’s the idea that human beings are just an evolutionary accident. But...Read more
The world of plants can be a dangerous place. Gorgeous monkshood, with stalks of purple blooms can cause delusions and death. A plump cashew can make you miserable if it isn't steamed properly. And aconite, almost indistinguishable from parsley can cause paralysis and stop your beating heart...Read more
Failure is a four letter word in America. Most of us do everything we can to avoid it. But what if we've got the wrong idea about failure - and it's all a matter of learning the right way to do it? This hour, one psychologist's take on how to embrace the fall. And comedian...Read more
Atheists are finally coming out of the closet, and in some cases denouncing religion. Others still crave a sense of the sacred even though they don’t believe in God. Do atheists have something to learn from religion? Why do so many people call themselves "spiritual but not religious"? And...Read more
Modern medicine can treat disease at a molecular—or even atomic – level. And today’s surgeons can fix things the naked eye can’t even see. But there’s one thing every patient wants that no technology in the world can provide: compassion. In this hour, doctors talk about the...Read more
When do we most need our leaders? In times of crisis? In times of war? In this hour of To the Best of Our Knowledge Winston Churchill's biographer Martin Gilbert explains how the man who offered his nation only blood, sweat, toil and tears made it believe that was enough. And he says Churchill's...Read more
Future Perfect: Dreamers, Schemers & Visionaries
Part Three
Our environment is in trouble. It's not hard to imagine global catastrophe as problems like climate change and overpopulation take their toll. But there's always hope...Read more
There's been a hot spotlight shining down on women this past year. From allegations of a war on women to the debate about reproductive rights, it's hard to tell how far women have come and just where they're going. So, what does feminism look like today? The first woman governor...Read more
Maybe you can sing like Jennifer Lopez or Ricky Martin. If not, looking like them is the next best thing. Right now, it’s never been cooler to be Hispanic. In this hour of To the Best of Our Knowledge, the Latino Revolution. From the rise of Latino-chic to the spicy secretes of salsa. ...Read more