Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
The bitter chill of winter can be hard to take. But there are people who love all that snow and ice; in fact, some don’t know anything else. In this hour of To the Best of Our Knowledge we’ll explore the Far North, from the Inuit of Greenland to the bears of Alaska. Also, a musical comedy...Read more
Read any good life-list books lately? How about "1,000 Places You Must Visit Before You Die?" or "1,001 Movies You Must See Before You Die." There's no shortage of "life-list" books to read these days. What's next? "1,000 Life-List Books You Must Read Before You Die"? Probably. We'll explore...Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
Think that a TV series based on the Coen Brothers' 1996 black comedy crime thriller, "Fargo," is a bad idea? Then you haven't seen "Fargo," The TV series. Creator and showrunner Noah Hawley talks about how he transformed the iconic film into the critically-acclaimed, award-winning TV series.Read more
Nicola Griffith wanted to fight back. A lesbian activist well-versed in the martial arts, Griffith knew she had the moves. But when her friend was attacked in a bar, she couldn't bring herself to hurt her attacker. In this hour of To the Best of Our Knowledge, the deadly, deep-minded lesbian...Read more
One day, an IRS auditor named Harold Crick wakes up to discover a voice in his head – a female voice narrating his life. That's the premise of the film, "Stranger Than Fiction." In this hour of To the Best of Our Knowledge, we'll meet the man who wrote the screenplay. Also, the story of Orson...Read more
Christopher Hogwood was not your ordinary household pet. For one thing, he weighed 700 pounds. And he loved to drink beer. Christopher was a very large pig with a heart of gold. In this hour of To the Best of Our Knowledge, the story of how Christopher Hogwood became the best-loved pig in...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
Woody Allen is an Academy Award-winning film-maker and screenwriter, but he's notoriously media-shy. In this hour of To the Best of Our Knowledge, Eric Lax on talking to Woody Allen over 36 years. Also, we'll explore how independent screenplays work.Read more
What happens when a Little League game turns into an epic battle to save the world from an evil, shape-shifting Coyote, and the fate of the Universe hangs on an 11-year-old boy? In this hour of To the Best of Our Knowledge, kids books for adults. Also, remembering L. Frank Baum, the creator of...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Elephants mourning their dead. Chimpanzees dying of grief. And the everyday joy of a dog at play. Biologist Marc Bekoff says the evidence is all around us, if we learn how to see it. In this hour of To the Best of Our Knowledge, the case for animal emotions. And we’ll spend some time with a...Read more
Grim news from Africa is easy to find, but there are good things happening there too. The creator of the Number 1 Ladies’ Detective Agency wants you to know all about them. He calls himself a Utopian writer. In this hour of To the Best of Our Knowledge, we’ll visit the real Botswana with...Read more
From Soup to Nuts:
Part Three
Meat and Potatoes isn't just what's for dinner. Meat and Potatoes is a way of life. In this hour of To the Best of Our Knowledge, food that sticks to your ribs. We'll get into the science of the French fry and...Read more
Wouldn't it be great if we could predict the future? We could invest wisely, prepare for social change, and have next season's fashionable footwear.
But in our accelerated world, it seems increasingly difficult to figure out what the next big thing will be. In this hour, are trends a...Read more
The average American spends more time on Facebook than with their pets or exercising -- and that's not counting Twitter, Instagram, or Vine. We're more connected than ever these days, but at what cost?Read more
The past is nebulous - a place no one can go. When we try to get our bearings there, we often find more than one truth. In this hour of To the Best of Our Knowledge, we’ll go back to Vietnam with Senator Bob Kerrey. And, one woman pieces together her past in war-torn Liberia. Also, paying...Read more
It's not quite the Manhattan that we're familiar with. "The New York Times" is available in a "War-Free Edition" and there are rumors of an escaped tiger on the prowl in the Upper East Side. This is the setting of Jonathan Lethem's critically-acclaimed new novel, "Chronic City." On this To the...Read more
In this hour of To the Best of Our Knowledge one man’s attempt to apologize for the sins of his family’s past. Also, mizuko kuyo, the Japanese ritural ceremony of apology to aborted fetuses. What does it mean to say “I’m sorry.”Read more
Vaclav Havel is President of the Czech Republic, but for many around the world, he's known as the poet in blue jeans, the dissident playwright who inspired a Velvet Revolution. On this hour of To the Best of Our Knowledge, President Havel talks art and politics. And, we'll go back to when the...Read more
Anne D. LeClaire was walking along the beach on Nantucket Sound when she heard a voice. The voice said, "Sit in silence." LeClaire turned to look but there was no one there. Anne D. LeClaire talks about this experience seventeen years ago and how it inspired her to remain silent for two days...Read more
Two years ago a professor in Wisconsin checked her mail and found a most unusual letter...from an Iraqi graduate student asking for scholarly advice. Since then professor Susan Friedman has exchanged hundreds of e-mails with academics in Iraq. And she's heard harrowing accounts of academic...Read more
This hour we combine two seemingly unlikely things: food and death. But when you think about it food and death really do go hand-in-hand. From the Last Meal to the new phenomenon of Death Dinners. Read more