Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
The Meaning of Life
Part Two
Karen Armstrong was a Catholic nun who stopped believing. In this hour of the Peabody Award-winning program To the Best of Our Knowledge, Armstrong shares her story of how she found her way back to God...Read more
Anne D. LeClaire was walking along the beach on Nantucket Sound when she heard a voice. The voice said, "Sit in silence." LeClaire turned to look but there was no one there. Anne D. LeClaire talks about this experience seventeen years ago and how it inspired her to remain silent for two days...Read more
The Mississippi River is an American icon. It's a body of water that’s been shaped as much by cultural processes as by environmental ones. From the state lines it draws to its role in literature and the arts, it’s a river that flows deep in the American psyche.
This episode is about the...Read more
TTBOOK staffers share some of our favorite interviews and shows produced by our favorite Canadian. Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
Plato argued that poets would be banished from the ideal republic. He said poets are only good for promoting petty emotions, such as anger and lust and love. In this hour of To the Best of Our Knowledge, poetry. We'll talk with four-time Slam Poet champion Patricia Smith about how powerful words...Read more
It's the sesquicentennial of the Civil War -- it's been 150 years since that epic war began. Americans will commemorate and remember it from different points of view. In this hour of To the Best of Our Knowledge, Remembering the Civil War. We'll talk about soldiers' experiences on the...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
In this hour of To the Best of Our Knowledge, a visit with former Israeli commando Uri Avnery, who went on to become an outspoken critic of Israeli policy. He's seen his office bombed. He's been beaten and once barely survived an assassination attempt. Today Avnery is calling for a separate...Read more
If grocery shopping isn’t your thing, here’s a new way to put food on the table: try sticking your arm under a rock until a big ol’ catfish clamps onto to you. In this hour of To the Best of Our Knowledge, noodling for catfish and other southern pastimes. Also, Texas singer Steve Earle’s...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Creativity is a little like obscenity: You know it when you see it, but you can't exactly define it....unless you're a neuroscientist. In labs around the...Read more
Computers permeate our lives. They scan our groceries. They entertain us. They keep us safe. But, can they write a poem? In this hour of To the Best of Our Knowledge, will your desktop be the next Bard? And, the life of the original rock n’ roll rebel: the 19th century French poet Arthur...Read more
What if our lives were like DVDs? What if we had alternative endings to look forward to, instead of death? We explore our lust for immortality. And we look at the many alternative endings that Ernest Hemingway wrote for his classic novel, "A Farewell to Arms."
Bohemians used to hate anything that reeked of money. It destroyed the soul. Now, many self-styled bohemians are reveling in slate shower stalls, Range Rovers, and lava-rock grills. In this hour of To the Best of Our Knowledge, the triumphs of the “Bobo” – the Bourgeois...Read more
Suppose there's a pill that would dramatically boost your creativity. Would you take it? Psychologist Jim Fadiman says that pill exists. It's the powerful hallucinogen LSD. Fadiman describes a remarkable experiment showing how psychedelics enhanced the creativity of senior scientists. Read more
In the history of near-fame experiences, one story stands out. Pete Best was the Beatles’ drummer just a few months before “Love Me Do” became a smash hit. His replacement, Ringo Starr, became a huge star. And Pete Best? He worked for decades as a civil servant in Liverpool. In this hour of...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
Mary Ann Caws is an internationally respected scholar of surrealism. She has translated many of the movements major texts and is the editor of “Surrealism (Themes and Movements).” Caws talks with Anne Strainchamps about the history of the surrealist movement. Also, we hear actor Steve O’Connell...Read more
James Tiptree Jr. wrote some of the most critically-acclaimed science fiction stories in the 1960's and 1970's....classics like "Houston, Houston, Do You Read?" and "The Women Men Don't See." But James Tiptree was actually the pseudonym of a 61-year-old woman, Alice B. Sheldon. In this hour of...Read more
Remember those great cars from the Fifties? The Redscare Phantom Witchhunter and the Bongo Beatnik Ferlinghetti TurboHipster? If you don’t recall them rolling off Detroit’s assembly lines, there’s a perfectly good reason. They never existed, except in the imagination of writer and illustrator...Read more