Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
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Episode Archives
As the Zika virus continues to make headlines, consensus is slowly growing among scientists that it’s showdown time for the mosquito. Time to marshal the technology to wipe them off the face of the earth. Which seems pretty extreme. Doesn’t it?
So, should we bio-...Read more
Physicist Lawrence Krauss says science can finally explain the age-old mystery: How can something come out of nothing? Or, to be more specific, how can the Big Bang pop out of empty space? Krauss also set off an intellectual brawl by saying theologians and philosphers have nothing...Read more
Christopher Hogwood was not your ordinary household pet. For one thing, he weighed 700 pounds. And he loved to drink beer. Christopher was a very large pig with a heart of gold. In this hour of To the Best of Our Knowledge, the story of how Christopher Hogwood became the best-loved pig in...Read more
Fifty Years ago James Watson and Francis Crick made history when they cracked the code for DNA. Watson was only 24 years old, and by no means the smartest scientist around. So why do some scientists make great discoveries? In this hour of To the Best of Our Knowledge, James Watson talks about...Read more
Everyone in your Facebook feed is falling for fake news–sharing it even when there's no way it can be true. They keep falling for it. But not you, right? You’re smart, well-educated. You can tell the difference. Or can you?Read more
James Tiptree Jr. wrote some of the most critically-acclaimed science fiction stories in the 1960's and 1970's....classics like "Houston, Houston, Do You Read?" and "The Women Men Don't See." But James Tiptree was actually the pseudonym of a 61-year-old woman, Alice B. Sheldon. In this hour of...Read more
Do you ever have a right to kill? What about Israeli agents who assassinate Hamas leaders? Or suicide bombers who blow up their enemies? Do the ends justify the means? William Vollman has written a three-thousand page treatise on the morality of violence. In this hour of To the Best of Our...Read more
Remember those great cars from the Fifties? The Redscare Phantom Witchhunter and the Bongo Beatnik Ferlinghetti TurboHipster? If you don’t recall them rolling off Detroit’s assembly lines, there’s a perfectly good reason. They never existed, except in the imagination of writer and illustrator...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
Ok, take a breath. Close your eyes. Recall the home of your childhood. Can you smell the cookies in the kitchen? Can you open a drawer in your bedroom? Do you see the sunlight through a window? Every building has a story. . . And not only a story, every building has a sound.Read more
Is there such a thing as true, original creativity? Or "Are we just seeing further by standing on the shoulders of giants?", to paraphrase Sir Isaac Newton. In this hour of To the Best of Our Knowledge we'll explore the question of where good ideas come from. Steven Johnson will tell us about...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
Is there anything science won’t tackle? The latest question neuroscientists are taking on is, “What makes something beautiful?” We're checking in with the scientists, the philosophers and the artists in this hour.Read more
Take a stroll through a natural history museum these days and you’ll not only see dinosaurs, you’ll smell them. Get a whiff of T-rex’s halitosis, his dinner leftovers, and, well, how should I put this – his droppings, too! In this hour of To the Best of Our Knowledge, museums that tickle your...Read more
Do you get eight hours of sleep a night? If not, join the millions of sleep-deprived Americans stumbling through life half-awake. Scientists say our national sleep debt may be behind the epidemics of diabetes and obesity – maybe even cancer. In this hour of To the Best of Our...Read more
“We can be bought,” they said,” but we can’t be bored.” The king and queen of American theater, Alfred Lunt and Lynn Fontanne turned down a fantastic sum from the movies in the middle of the depression to continue to live their illusion on the stage. In this hour of To the Best of Our...Read more
Say you’re in Vegas playing high-stakes poker. You haven’t slept in days. To make matters worse, you’re being stared down by two of the best poker players in the world. And...you’re bluffing. So, you bet it all to bring the pot to well over a million dollars. In this hour of To the Best of...Read more
Many Americans think the story of Cuba begins and ends with Fidel Castro. But the soul of the Cuban Revolution belonged to the charismatic, Romantic guerilla hero Ernesto “Che” Guevara. To the Best of Our Knowledge revisits the Sixties and counts the private costs of that era’s social gains. ...Read more
Governors are slashing state spending, and the President has put some of his own party's favorite programs on the chopping block. But how much of the new austerity is really necessary, and how much is politics? In this hour of To the Best of Our Knowledge, is austerity a dangerous idea? Join...Read more
He was a wandering pilgrim who talked to birds, healed the sick and tamed wild beasts. He was also the closest thing to a medieval rock star - a man so revered in his lifetime that people tore at this clothes, desperate to touch a living saint. Today, St. Francis of Assisi is admired by both...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more