Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
If you ever find yourself on a dark country road in Ireland, bring along some salt, red thread, and a cross. That’s what you’ll need to protect yourself from “the other crowd.” Next time on To the Best of Our Knowledge, the fairies of Ireland. They’re magical, vengeful, and still alive and...Read more
After 11 years of isolation in New England, Nathan Zuckerman returns to New York City. Now 71, Zuckerman discovers that a lot has changed. In this hour of To the Best of Our Knowledge, we'll meet Nathan Zuckerman's creator, the renowned novelist, Philip Roth. And we'll find out how both Roth...Read more
Samuel Adams couldn’t ride a horse to save his life, and had a tendency to drool. As if that’s not bad enough, John Adams was a roly-poly fellow who spent his free time fantasizing about becoming the next American King. In this hour of To the Best of Our Knowledge, a revisionist’s take on the...Read more
What is it about certain films, and certain directors, that inspires obsession? Maybe because these directors are obsessed themselves. Like the legendary filmmaker Werner Herzog, who...Read more
In this hour of To the Best of Our Knowledge, some of the most critical questions you’ll ever face. Who are you? What does your life mean? And how did you decide who you wanted to be? We’ll hear from Rabbi Harold Kushner, Senator John McCain and novelist Tim O’Brien. We’ll talk about making...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
The world of plants can be a dangerous place. Gorgeous monkshood, with stalks of purple blooms can cause delusions and death. A plump cashew can make you miserable if it isn't steamed properly. And aconite, almost indistinguishable from parsley can cause paralysis and stop your beating heart...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
One of the biggest challenges a journalist can face is reporting a story when your connection to your source is compromised. They won't talk, or they can't talk, or it's your own father. Can anyone ever uncover the truth, the whole truth, about another person?Read more
Your name is a collection of sounds and syllables that identify you. It's your tag, handle, label, second skin. It's written on your birth certificate and it'll be inscribed on your grave. But what does it actually mean? Names carry family dreams, expectations and legacies....Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
Celebrate Midsummer's Eve with a visit to the fey folk. In this hour of To the Best of Our Knowledge, we'll have an hour filled with stories of changelings and other-kin, Fairy Courts and green children. We'll conjure up a world of enchantment, but beware! There are no Tinkerbells in the world....Read more
Here’s the truth: the wild romance will probably end. Wedding vows, intimacy, heartache… they can have a long shelf-life. But those butterflies in your stomach? Wild libidinal longings? They tend to quiet over time.
So what happens after the romance ends? From passionate marriage, to ...Read more
From the minute we can pick up a crayon, most of us want to draw something - a house, a tree, the sun. As we get older we aim for nuance and sophistication - landscapes and shadows, faces and expressions. A gifted few will achieve something greater - they’ll make art. On this hour of To the...Read more
There’s a powerful new voting bloc in America. They’re white, working class, and they live in places that have been left behind. We'll talk with "Hillbilly Elegy" author J.D. Vance, and country music star Brandy Clark joins us in the studio to play some music and talk about her hometown.Read more
Television used to be formulaic. Today, it’s the best gig around. We examine the explosion of high quality TV, from The Sopranos and The Wire to Mad Men, and talk with the creator of HBO’s True Detective.Read more
Graphic novelist Neil Gaiman has a talent for creating strange and fantastic worlds. His “Sandman” comic books helped spawn the Goth movement, and with characters called Dream and Death, he created a new mythology. In this hour of To the Best of Our Knowledge, we’ll visit with Neil Gaiman at...Read more
For millions of people, a mosque is a safe haven, a place to worship. But others fear that mosques are a breeding ground for terrorists — especially since September 11, 2001. It's the same building, but has become a marker for so much controversy.
This hour, we wanted to approach the...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
Every year, Americans spend billions of dollars to try to improve themselves. They buy books and CDs, go to seminars...some even walk over hot coals in their bare feet. In this hour of To the Best of Our Knowledge, we'll try to find out if the self-help movement is really helping us.Read more
Mary Ann Caws is an internationally respected scholar of surrealism. She has translated many of the movements major texts and is the editor of “Surrealism (Themes and Movements).” Caws talks with Anne Strainchamps about the history of the surrealist movement. Also, we hear actor Steve O’Connell...Read more