Can science conquer death? It may seem like an absurd question, but some people think it's possible. In this hour of To The Best Of Our Knowledge, we'll meet Aubrey de Grey, a maverick English scientist who's identified seven major kinds of molecular and cellular damage. He thinks we can prevent...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Calling Lynne Cox a swimmer is like calling Mohammed Ali a tough guy. At age fourteen, she swam to Catalina Island from mainland California. At eighteen she swam between the islands of New Zealand. Years later, with miles of hard swims behind her, she turned her eye to the unthinkable - the...Read more
Ben Kilham has some unusual playmates - black balls of fur who scratch, wrestle and climb all over him. They are orphaned bear cubs. And Kilham is their surrogate mom. He’s raised two dozen bear cubs and then released them into the wild. Next time on To the Best of Our Knowledge, we’ll trek...Read more
It seems everyone has something to say about motherhood. A lot of people have advice. Others just have... issues. In this hour of To The Best of Our Knowledge -- the tricky topic of motherhood. Linda Gray Sexton remembers her mother, the troubled poet Anne...Read more
Phil Harvey gives away tens of millions of dollars every year to fight AIDS and promote family planning in such places as India, Brazil, Vietnam and Ethiopia. Where does the money come from? Harvey runs the largest mail-order erotica business in the world. In this hour of To the Best of Our...Read more
Malcolm Gladwell knows how to succeed in show business without really trying -- write a story for The New Yorker about a psychiatrist who studies serial killers. Then a playwright will take some of the words from your article and use them in a Broadway play. Next time on To the Best of Our...Read more
Forty years ago, the U.S. ended its war in Vietnam, but we're still fighting over its legacy - in foreign policy and military strategy, and also in books and movies. But there's one question Americans rarely ask: what does the war mean to the Vietnamese themselves? We'll hear several...Read more
It’s one of the great stories in the history of books. James Murray was a poor kid from Scotland who dropped out of school at age 14. Somehow, he taught himself the history of words in various languages, and went on to create the world’s greatest dictionary. In this hour of To the Best of Our...Read more
It used to be that comics were just for kids. Today, we call them "graphic novels," and they're one of the fastest growing forms of American literature. In this hour of To the Best of Our Knowledge, how graphic art grew up...with Will Eisner's biographer, Jules Feiffer, Dennis Kitchen, and...Read more
If you think about it, every day we receive countless services from complete strangers — the newspaper delivered to your door, the trash picked up at the crack of dawn, the fresh fruit for sale at the supermarket. There's a whole army of invisible workers powering our economy who we rarely get...Read more
Words can change lives. Just look at the “at-risk” students in Erin Gruwell’s class. Many of them were branded “unteachable.” Then they read Anne Frank’s diary, and started to keep their own journals. The experience was electrifying. In this hour of To the Best of...Read more
After 11 years of isolation in New England, Nathan Zuckerman returns to New York City. Now 71, Zuckerman discovers that a lot has changed. In this hour of To the Best of Our Knowledge, we'll meet Nathan Zuckerman's creator, the renowned novelist, Philip Roth. And we'll find out how both Roth...Read more
It doesn’t get much more American than a waitress in a diner taking your order. In this hour of To the Best of Our Knowledge, the diner. For some, like painter Edward Hopper, the diner is a muse. For others it’s just a greasy spoon. But have we romanticized the endless cups of coffee and the...Read more
Film on radio? Why not? This hour, join us LIVE from the historic Orpheum Theatre in Madison, Wisconsin, for a special “Wisconsin Film Festival edition” of To The Best of Our Knowledge for film on radio. We’ll talk Dogme with “Italian for Beginners” director, Lone Scherfig. Also, the anti-...Read more
With hundreds of millions of people moving into cities, we're wondering what shapes urban cultures. In this hour, Nobel Laureate Orhan Pamuk talks about how Istanbul shaped his writing. One historian argues that early liberal philosophies from Amsterdam shaped the United States. And we check in...Read more
Is there anything science won’t tackle? The latest question neuroscientists are taking on is, “What makes something beautiful?” We're checking in with the scientists, the philosophers and the artists in this hour.Read more
What is it about certain films, and certain directors, that inspires obsession? Maybe because these directors are obsessed themselves. Like the legendary filmmaker Werner Herzog, who...Read more
Take a stroll through a natural history museum these days and you’ll not only see dinosaurs, you’ll smell them. Get a whiff of T-rex’s halitosis, his dinner leftovers, and, well, how should I put this – his droppings, too! In this hour of To the Best of Our Knowledge, museums that tickle your...Read more
In this hour of To the Best of Our Knowledge, some of the most critical questions you’ll ever face. Who are you? What does your life mean? And how did you decide who you wanted to be? We’ll hear from Rabbi Harold Kushner, Senator John McCain and novelist Tim O’Brien. We’ll talk about making...Read more
James Tiptree Jr. wrote some of the most critically-acclaimed science fiction stories in the 1960's and 1970's....classics like "Houston, Houston, Do You Read?" and "The Women Men Don't See." But James Tiptree was actually the pseudonym of a 61-year-old woman, Alice B. Sheldon. In this hour of...Read more
Remember those great cars from the Fifties? The Redscare Phantom Witchhunter and the Bongo Beatnik Ferlinghetti TurboHipster? If you don’t recall them rolling off Detroit’s assembly lines, there’s a perfectly good reason. They never existed, except in the imagination of writer and illustrator...Read more
As artists and scientists explore the edges of our senses, what we touch, taste, see, smell, and hear is changing.
In this hour we hear from a psychiatrist who’s using touch to help people recover from trauma, investigate a mysterious sensory experience that gives some people euphoric...Read more
Suppose neuroscientists map the billions of neural circuits in the human brain....are we any closer to cracking the great existential mysteries - like meaning,...Read more
Investigative journalist Seymour Hersh made his name when he broke the story of the My Lai Massacre. Looking back you have to wonder: why did Lt. William Calley tell Hersh he’d killed hundreds of Vietnamese civilians? On this hour of To the Best of Our Knowledge Hersh says “because I asked him...Read more