Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
Electrons to Enlightenment
Part Three
One of the Dalai Lama's favorite places in America is a neuro-biology lab at the University of Wisconsin, looking for scientific proof that meditation works. In other labs across the country,...Read more
We’ve heard a lot about Islamic fundamentalists who hate the West. Some people can’t wait for the United States to invade Afghanistan. But no one would be happier to see the back of Osama bin Laden than the Average Afghan. In this hour of To the Best of Our Knowledge, the crucial...Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
Uncovering the real story in Iraq is getting harder. Western journalists have become targets, just like American soldiers. And reporters now take elaborate precautions to avoid being killed or kidnaped. In this hour of To the Best of Our Knowledge we'll talk about the hazards of war reporting...Read more
Her novel “Bel Canto” was a hit so now novelist Ann Patchett is a star. But back when they were in college, it was her fellow student Lucy Grealy who got treated like a rock star. In this hour of To the Best of Our Knowledge, a look at uncommon friendships. Ann Patchett tells how her...Read more
Where’s James Bond when you need him? You have to wonder about the spy business after the dubious information that was used to justify America’s war against Iraq. In this hour of To the Best of Our Knowledge, an argument for revealing all the secrets to the public. And, a look back at Anthony...Read more
“Good fences make good neighbors." Robert Frost writes in Mending Wall. Is he right? Maybe homemade chocolate chip cookies or lending a lawnmower are more neighborly. I guess it depends on who your neighbors are.Read more
You know the earth is round, the sky is up, and your dog loves you. But HOW do you know those things? This week, how we form opinions – the psychology and brain chemistry behind our beliefs.Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
For decades “imperialism” was a dirty word, and all talk of empire seemed old-fashioned. Now some people say a new empire has emerged – the American Empire. But is America’s unrivaled power good for the world? In this hour of To the Best of Our Knowledge, the debate over American supremacy. ...Read more
"The statistics on sanity are that one out of every four Americans is suffering from some form of mental illness. Think of your three best friends. If they're okay, then it's you."...Read more
Salman Rushdie's new novel is called "The Enchantress of Florence." It's a tale of two cities, consisting of stories tucked inside stories tucked inside stories...along the lines of Scheherazade's stories of "One Thousand and One Nights." In this hour of To the Best of Our Knowledge, Salman...Read more
In this hour of To the Best of Our Knowledge, Russia and China. They were the two Communist giants. Now each is carving out a new future. By most accounts, China is doing it better. It’s still an authoritarian state, but the economy if booming. And Russia? Well, it’s capitalism’s wild...Read more
TTBOOK staffers share some of our favorite interviews and shows produced by our favorite Canadian. Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
Read any good life-list books lately? How about "1,000 Places You Must Visit Before You Die?" or "1,001 Movies You Must See Before You Die." There's no shortage of "life-list" books to read these days. What's next? "1,000 Life-List Books You Must Read Before You Die"? Probably. We'll explore...Read more
Everyone knows what comic books are about, right? But it's not all about people in long underwear hitting each other. This hour on To the Best of Our Knowledge, heroes, anti-heroes, and regular folks strutting their stuff in black and white.Read more
Think that a TV series based on the Coen Brothers' 1996 black comedy crime thriller, "Fargo," is a bad idea? Then you haven't seen "Fargo," The TV series. Creator and showrunner Noah Hawley talks about how he transformed the iconic film into the critically-acclaimed, award-winning TV series.Read more
Seven hundred million people get their music from the Internet. More than 10 million people own iPods. Does this mean that compact discs and record companies are going the way of the gramophone and eight-track tapes? In this hour of To the Best of Our Knowledge, we'll look at this digital...Read more
This hour we combine two seemingly unlikely things: food and death. But when you think about it food and death really do go hand-in-hand. From the Last Meal to the new phenomenon of Death Dinners. Read more
Start telling love stories and chances are, you’ll find yourself telling tales of transgression. In this hour of To the Best of Our Knowledge, Joyce Carol Oates talks about the harm done by family secrets. P.D. James muses on why women are so good at crime fiction. A...Read more
Are you a knave? Scalawag? A varlet? Are you a scoundrel? Maybe you’re not but secretly you want to be. Being a scoundrel kind of has a ring to it. It’s romantic. Rebellious.Read more