Paul Ewald is a cancer researcher. He says we're entering a golden era in cancer treatment based on one emerging idea: most cancers are caused by viruses. It's good news, according to Ewald, who says we'll be able to treat cancer preventively, with vaccines. In this hour of To the Best of Our...Read more
Intelligent. Optimistic. Curious.
Episode Archives
For decades “imperialism” was a dirty word, and all talk of empire seemed old-fashioned. Now some people say a new empire has emerged – the American Empire. But is America’s unrivaled power good for the world? In this hour of To the Best of Our Knowledge, the debate over American supremacy. ...Read more
Who would have guessed that number two on the Best Seller List this summer would be an intellectual thriller starring four brainy Princeton seniors and a 15th century manuscript written in code? In this hour of To the Best of Our Knowledge, meet the authors of “The Rule of Four.” Lost and...Read more
Who's calling your shots? Who's in charge of your thinking, your perceptions? Maybe it's simple. Your mind is the boss, then your brain runs your body. Everything's fine. Until it's not and you find yourself confronting depression or autism or a head injury that leaves you with brain damage....Read more
Chaotic headlines out of Washington, ice melting in Antarctica, world temps rising and global conflict on the rise… it could be worse. It could be Ragnarok. Writer Neil Gaiman retells the ancient Norse myth of the Twilight of the Gods and apocalyptic end of the world in his stunning new...Read more
Salman Rushdie's new novel is called "The Enchantress of Florence." It's a tale of two cities, consisting of stories tucked inside stories tucked inside stories...along the lines of Scheherazade's stories of "One Thousand and One Nights." In this hour of To the Best of Our Knowledge, Salman...Read more
Are humans innately violent? If you stripped the civilization out of us, just how bad would we be?Read more
In this hour of To the Best of Our Knowledge, Russia and China. They were the two Communist giants. Now each is carving out a new future. By most accounts, China is doing it better. It’s still an authoritarian state, but the economy if booming. And Russia? Well, it’s capitalism’s wild...Read more
On February 13th, 1945 Kurt Vonnegut and other American POWs were hiding in a cellar during the firebombing of Dresden. They were remarkably lucky, as 135,000 people died that night. During the bombing one soldier said, “I wonder what the poor people are doing tonight?” Nobody laughed but, as...Read more
Chris Ayres never wanted to cover the war. He was perfectly content reporting on celebrity gossip in L.A. But through a twist of fate, he found himself embedded with Marines in Iraq, living in a Humvee and waiting for his death at the hands of the Republican Guard. In this hour of To the Best...Read more
There’s another September 11th. On that day thirty years ago, a military coup overthrew Chile’s elected president, Salvador Allende. Newly declassified documents show the C.I.A.’s extensive involvement in the coup. On this hour of To the Best of Our Knowledge, the Pinochet file. Also,...Read more
When we’ve had enough of reality, we often seek escape in a movie. But we don’t have to shut off our brains when we visit the cinema. Some films actually encourage us to use our minds. This hour, we explore philosophy through the lens of filmRead more
Reading a good book may be the most fun you can have sitting down. Books can be a hobby or a passion, an interest or an obsession. In this hour of To the Best of Our Knowledge, tales from book world. A former bookseller takes us to Hay on Wye - the Welsh town that’s well on its way to...Read more
Want to learn a second or third language? You don’t have to slave away in a French seminar – it only takes a minute or two to pick up “ob.” Next time on tob-oo thob-ah bob-est ob-of ob-our knob-ow-lob-edge. Or should I say To the Best of Our Knowledge, word games, and secret...Read more
There's something magical about making words. Ask any parent what their baby's first word was. Chances are they'll remember. Words are what set us apart from all the other animals. And they're endlessly fascinating. In this hour of To Best of Our Knowledge we'll meet a variety of people...Read more
In 1945 Franklin Roosevelt worked out a deal with the king of Saudi Arabia. America got unlimited access to Saudi Oil, and in return, the U.S. protected the Royal Family against its enemies. Now that special relationship is under fire. In this hour of To the Best of Our Knowledge, the politics...Read more
"The statistics on sanity are that one out of every four Americans is suffering from some form of mental illness. Think of your three best friends. If they're okay, then it's you."...Read more
In the wake of a number of high profile shootings over the past year, people are talking about policing, racism, and injustice. But there's one issue we don't really talk all that much about: fear.This hour, we take a closer look at negative stereotypes about African American men, how those...Read more
Good house-keeping used to go hand-in-hand with good citizenship. And remember the phrase, "cleanliness is next to godliness"? In this hour of To the Best of Our Knowledge, thoughts on the art of keeping house. We'll talk about the science of dust, meet the Queen of Clutter, and hear novelist...Read more
"Shhh… I have a secret… Now, I could tell you but then I'd have to kill you." Classic spy joke – but not so funny when it's true. In this hour of To The Best of Our Knowledge, we'll go the dark side of secrecy - warrantless wiretapping, secret CIA prisons, "extraordinary rendition,"...Read more
Grim news from Africa is easy to find, but there are good things happening there too. The creator of the Number 1 Ladies’ Detective Agency wants you to know all about them. He calls himself a Utopian writer. In this hour of To the Best of Our Knowledge, we’ll visit the real Botswana with...Read more
Wouldn't it be great if we could predict the future? We could invest wisely, prepare for social change, and have next season's fashionable footwear.
But in our accelerated world, it seems increasingly difficult to figure out what the next big thing will be. In this hour, are trends a...Read more
This hour we combine two seemingly unlikely things: food and death. But when you think about it food and death really do go hand-in-hand. From the Last Meal to the new phenomenon of Death Dinners. Read more
Toby Young thought he had it made. He had a prestigious job at Vanity Fair magazine, a press pass that got him in everywhere, and a suave British accent to boot. He was poised to take Manhattan. Then everything went wrong. In this hour of To the Best of Our Knowledge, flops, failures and...Read more